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Effect of Intermittent and Continuous Theta Burst Stimulation on Sleep, Daytime Sleepiness, and Fatigue in Depression
Sponsor: Jakub Antczak
Summary
Intermittent and continuous theta-burst stimulation (iTBS and cTBS respectively) are the newer modalities of transcranial magnetic stimulation with documented efficacy in treatment of depressed mood but with conflicting results regarding their efficacy in treatment of other symptoms of depression such as insomnia, daytime sleepiness and fatigue. This study will investigate the efficacy of iTBS over the left dorsolateral prefrontal cortex (DLPFC) and cTBS over the right DLPFC, compared to sham stimulation, in treatment of insomnia, daytime sleepiness and fatigue in depression.
Official title: Effect of Intermittent and Continuous Theta Burst Stimulation on Sleep Quality, Sleep Propensity, Daytime Sleepiness, and Fatigue in Depression
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
90
Start Date
2024-05-15
Completion Date
2027-05
Last Updated
2024-10-15
Healthy Volunteers
No
Conditions
Interventions
iTBS
Active iTBS over the left DLPFC to induce the long term potentiation of stimulated area.
cTBS
Active cTBS over the right DLPFC to induce the long term potentiation of stimulated area.
Sham
Sham iTBS or cTBS over the left or right DLPFC respectively for placebo.
Locations (1)
Institute of Psychiatry and Neurology
Warsaw, Poland