Clinical Research Directory

Inclusion Criteria: 1. Age 18-65 years old. 2. Meets the diagnostic criteria for allergic rhinitis. 3. rTNSS score greater than or equal to 6 points. 4. The subject or his/her legal representative gives informed consent, fully understands the purpose of the study, is able to communicate effectively with the investigator, and comprehends and complies with the requirements set forth in the study. \- Exclusion Criteria: 1. Patients with acute nasosinusitis or upper respiratory tract infection. 2. Patients diagnosed with chronic sinusitis, nasal septum deviation, nasal polyps, nasal tumors, and other nasal diseases or have undergone nasal surgery. 3. Antibiotics, PPI, probiotics, and other drugs that alter gut microbiota were used in the past two weeks. 4. Patients with poor lung function. 5. Patients with severe liver, kidney, and heart diseases 6. Patients with known psychiatric or neurological diseases. 7. Patients who use antihistamines, glucocorticoids, decongestants, mast cell membrane stabilizers, leukotriene antagonists in the past two weeks. 8. According to the judgment of the investigator, the subjects are not suitable to participate in this clinical study, or participation in this clinical study cannot guarantee the rights and interests of the subjects. \-