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Comparative Evaluation of Melatonin Versus MTA on Vital Pulp Therapy in Young Permanent First Molars: An in Vivo Study
Sponsor: Suez Canal University
Summary
The process of dental caries is dynamic and can be either reversible or irreversible depending on the balance between protective and pathologic factors in the oral cavity. Untreated dental caries causes pulpal injury, inflammation, and necrosis. Melatonin plays an essential role in the regulation of bone growth. The actions that melatonin exerts on odontoblasts may be similar to its action on osteoblasts.
Official title: Comparative Evaluation of Melatonin Versus Mineral Trioxide Aggregate on Vital Pulp Therapy in Young Permanent First Molars: An in Vivo Study
Key Details
Gender
All
Age Range
6 Years - 8 Years
Study Type
INTERVENTIONAL
Enrollment
45
Start Date
2023-05-20
Completion Date
2024-10-02
Last Updated
2024-08-02
Healthy Volunteers
Yes
Interventions
Mineral trioxide aggregate (dressing material)
MTA (Angulus Industrial de productus Odontologists S/a, Brazil) that applied on dental pulp for tissue regeneration
Melatonin (dressing material)
melatonin powder 250mg (sigma, Aldrich)- white powder mixing with saline and applied on dental pulp
Locations (1)
Faculty of Medicine, Suez canal university
Ismailia, Egypt