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Pulmonary Hypertension and Oxygen Saturation Targeting in Preterm Infants
Sponsor: University of Alabama at Birmingham
Summary
Around 50% of infants born extremely preterm develop a chronic lung disease known as bronchopulmonary dysplasia of which some infants will also develop pulmonary hypertension of which 50% of children will die before the age of 2. Physicians are currently limited in their ability to select the most appropriate oxygen targets that will improve outcomes in infants with this condition. This clinical trial will determine whether using different amounts of oxygen improve outcomes in infants with this disease.
Official title: Target Oxygen Saturation Ranges in Infants With Bronchopulmonary Dysplasia Associated Pulmonary Hypertension
Key Details
Gender
All
Age Range
1 Month - 5 Months
Study Type
INTERVENTIONAL
Enrollment
39
Start Date
2026-04
Completion Date
2030-07-01
Last Updated
2026-03-27
Healthy Volunteers
Yes
Interventions
higher oxygen saturation target using Nellcor pulse oximetry sensors
The intervention will be a cross over exposure to the higher oxygen saturation target.
lower oxygen saturation target using Nellcor pulse oximetry sensors
The intervention will be a cross over exposure to the lower oxygen saturation target.
Locations (2)
The University of Alabama at Birmingham
Birmingham, Alabama, United States
Yale New Haven Hospital
New Haven, Connecticut, United States