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RECRUITING
NCT06373679
NA

Switch or Quit R01

Sponsor: Medical University of South Carolina

View on ClinicalTrials.gov

Summary

This study evaluates whether non-cigarette tobacco products (e-cigarettes) can help smokers quit smoking as compared to traditional quit methods (nicotine replacement therapy or varenicline/Chantix). Participants in this study will be randomly assigned to one of two groups, then will have a choice between the offered products of that group. Participants in the e-cigarette group will have a choice of e-cigarette brand and flavor. Participants in the medication group will have choice between nicotine replacement therapy (patches and lozenges) or varenicline, also known as Chantix. Participation will last 6 months and will include weekly phone calls for the initial 7-weeks plus a 11-week phone call and a 6-month follow-up visit. Participants will also complete electronic daily diaries during the first 7-weeks.

Official title: Non-cigarette Tobacco Products as Harm Reduction Tools in Smokers Who Failed to Quit With Traditional Methods

Key Details

Gender

All

Age Range

21 Years - Any

Study Type

INTERVENTIONAL

Enrollment

225

Start Date

2024-07-10

Completion Date

2027-05-01

Last Updated

2025-07-25

Healthy Volunteers

Yes

Interventions

BEHAVIORAL

Switching to E-Cigarette

Participants will receive eleven weeks of e-cigarette products with instructions to switch completely at switch date

BEHAVIORAL

Switching using Medication

Participants will receive eleven weeks of FDA approved medication, either varenicline or combination NRT, with instructions to quit smoking cigarettes at quit date

Locations (1)

Medical Univeristy of South Carolina

Charleston, South Carolina, United States