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Switch or Quit R01
Sponsor: Medical University of South Carolina
Summary
This study evaluates whether non-cigarette tobacco products (e-cigarettes) can help smokers quit smoking as compared to traditional quit methods (nicotine replacement therapy or varenicline/Chantix). Participants in this study will be randomly assigned to one of two groups, then will have a choice between the offered products of that group. Participants in the e-cigarette group will have a choice of e-cigarette brand and flavor. Participants in the medication group will have choice between nicotine replacement therapy (patches and lozenges) or varenicline, also known as Chantix. Participation will last 6 months and will include weekly phone calls for the initial 7-weeks plus a 11-week phone call and a 6-month follow-up visit. Participants will also complete electronic daily diaries during the first 7-weeks.
Official title: Non-cigarette Tobacco Products as Harm Reduction Tools in Smokers Who Failed to Quit With Traditional Methods
Key Details
Gender
All
Age Range
21 Years - Any
Study Type
INTERVENTIONAL
Enrollment
225
Start Date
2024-07-10
Completion Date
2027-05-01
Last Updated
2025-07-25
Healthy Volunteers
Yes
Conditions
Interventions
Switching to E-Cigarette
Participants will receive eleven weeks of e-cigarette products with instructions to switch completely at switch date
Switching using Medication
Participants will receive eleven weeks of FDA approved medication, either varenicline or combination NRT, with instructions to quit smoking cigarettes at quit date
Locations (1)
Medical Univeristy of South Carolina
Charleston, South Carolina, United States