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ACTIVE NOT RECRUITING
NCT06374095

1 vs 7 RATG Infusions in Renal Transplantation

Sponsor: Mario Negri Institute for Pharmacological Research

View on ClinicalTrials.gov

Summary

This trial is to compare the risk/benefit profile over six-month follow-up of two induction immunosuppressive regimens based on one or seven low-dose perioperative RATG infusions on top of the same induction therapy with basiliximab and steroid (progressively tapered post-transplant) and maintenance therapy with calcineurin inhibitors and mycophenolate mofetil/mycophenolic acid in 75 recipients (25 Patients and 50 Reference-Patients) of a single or dual first kidney transplant from an ideal or marginal donor at a single Renal Transplant Center.

Official title: Basiliximab With One Day or Seven Days RATG Induction Therapy in Renal Transplantation: a Matched-cohort Observational Study

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

75

Start Date

2024-07-30

Completion Date

2025-09

Last Updated

2025-09-04

Healthy Volunteers

No

Interventions

DRUG

RATG

Thymoglobulin, Genzyme corporation, Italy.

DRUG

Basiliximab

Simulect, Novartis, Italy.

Locations (1)

ASST HPG23 - Unità di Nefrologia

Bergamo, BG, Italy