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1 vs 7 RATG Infusions in Renal Transplantation
Sponsor: Mario Negri Institute for Pharmacological Research
Summary
This trial is to compare the risk/benefit profile over six-month follow-up of two induction immunosuppressive regimens based on one or seven low-dose perioperative RATG infusions on top of the same induction therapy with basiliximab and steroid (progressively tapered post-transplant) and maintenance therapy with calcineurin inhibitors and mycophenolate mofetil/mycophenolic acid in 75 recipients (25 Patients and 50 Reference-Patients) of a single or dual first kidney transplant from an ideal or marginal donor at a single Renal Transplant Center.
Official title: Basiliximab With One Day or Seven Days RATG Induction Therapy in Renal Transplantation: a Matched-cohort Observational Study
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
75
Start Date
2024-07-30
Completion Date
2025-09
Last Updated
2025-09-04
Healthy Volunteers
No
Conditions
Interventions
RATG
Thymoglobulin, Genzyme corporation, Italy.
Basiliximab
Simulect, Novartis, Italy.
Locations (1)
ASST HPG23 - Unità di Nefrologia
Bergamo, BG, Italy