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Peer Support for Adolescents and Emerging Adults With Sickle Cell Pain
Sponsor: University of Pittsburgh
Summary
The study, known as the Peer suppoRt for adolescents and Emerging adults with Sickle cell pain: promoting ENgagement in Cognitive behavioral thErapy (PRESENCE), aims to determine the effectiveness of digital CBT in reducing pain, opioid use, and healthcare utilization among AYAs with SCD. It also seeks to understand the role of personalized peer support in enhancing engagement and outcomes of digital CBT interventions. By leveraging existing infrastructure for delivering virtual peer support interventions, tailored digital CBT programs for individuals with SCD, and partnerships with CBOs, the study aims to provide valuable insights into the feasibility and effectiveness of digital CBT as a pain management strategy for this vulnerable population.
Official title: Peer Support for Adolescents and Emerging Adults With Sickle Cell Pain: Promoting Engagement in Cognitive Behavioral Therapy
Key Details
Gender
All
Age Range
16 Years - 30 Years
Study Type
INTERVENTIONAL
Enrollment
470
Start Date
2025-03-10
Completion Date
2028-05
Last Updated
2026-01-07
Healthy Volunteers
No
Conditions
Interventions
CBT+ Health coach
Participants will complete the pre-enrollment clinical screening measures (PHQ-9M, GAD-7, and PEG-3) and will repeat those assessments, as well as outcome assessments, at 3 months, 6 months, and 12 months. Participants in CBT w/ Health coach group will engage with the CaRISMA app to complete a daily pain and mood e-diary, daily record of opiate use, and weekly assessment of pain via the Painimation tool. In addition participants will have weekly contact with a peer health coach.
CBT w/o Health Coach ( self-guided)
Participants will complete the pre-enrollment clinical screening measures (PHQ-9M, GAD-7, and PEG-3) and will repeat those assessments, as well as outcome assessments, at 3 months, 6 months, and 12 months. Participants CBT w/o Health coach groups will engage with the CaRISMA app to complete a daily pain and mood e-diary, daily record of opiate use, and weekly assessment of pain via the Painimation tool.
Usual Care
Participants will complete the pre-enrollment clinical screening measures (PHQ-9M, GAD-7, and PEG-3) and will repeat those assessments, as well as outcome assessments, at 3 months, 6 months, and 12 months. Participants in the UC group will be asked to engage with the CaRISMA app to complete a daily pain and mood e-diary, daily record of opiate use, and weekly assessment of pain via the Painimation tool. All other care will be at the discretion of their treating provider
Locations (14)
University of South Alabama Medical Center
Mobile, Alabama, United States
UCLA Mattel Children's Hospital Ronald Reagan Hospital
Los Angeles, California, United States
Connecticut Children's Medical Center
Hartford, Connecticut, United States
Children's Healthcare of Atlanta
Atlanta, Georgia, United States
Ann and Robert H. Lurie Children's Hospital of Chicago
Chicago, Illinois, United States
The Regents of the University of Michigan
Ann Arbor, Michigan, United States
Rutgers New Jersey Medical School
Newark, New Jersey, United States
Weil Cornell Medical College
New York, New York, United States
University of Rochester Medical Center
Rochester, New York, United States
Wake Forest Baptist Hospital
Durham, North Carolina, United States
East Carolina University Health Medical Center
Greenville, North Carolina, United States
UPMC University of Pittsburgh Classical Hematology Adult Clinic
Pittsburgh, Pennsylvania, United States
UPMC Children's Hospital of Pittsburgh
Pittsburgh, Pennsylvania, United States
Virginia Commonwealth University
Richmond, Virginia, United States