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Investigating the Plasticity of Human Predictive Coding Through Neuromodulation
Sponsor: Università Vita-Salute San Raffaele
Summary
The hypothesis of the study is to investigate how different trm (tES) methods (transcranial Alternating Current Stimulation, tACS, and transcranial Random Noise Stimulation, tRNS) applied at different stimulation frequencies and networks can modulate the predictive mechanisms in human perception and cognition. This is an interventional, monocentric, cross-sectional randomized, single-blinded study on healthy adult volunteers, recruited through online advertisements, flyers and oral transmission. Volunteers will be recruited from the general population of young adults.
Official title: Investigating the Plasticity of Human Predictive Coding Through Neuromodulation: an Interventional, Monocentric, Randomized, Single-blinded Study on Healthy Adult Volunteers
Key Details
Gender
All
Age Range
18 Years - 35 Years
Study Type
INTERVENTIONAL
Enrollment
210
Start Date
2024-06-13
Completion Date
2026-12-31
Last Updated
2024-06-14
Healthy Volunteers
Yes
Conditions
Interventions
Occipital tACS at IAF-2Hz
tACS applied to occipital areas at 2 Hz below the individual alpha frequency (IAF)
Occipital tACS at IAF+2Hz
tACS applied to occipital areas at 2 Hz above the individual alpha frequency (IAF)
Frontal tACS at 4-7 Hz
tACS applied to frontal areas at 4-7 Hz
Occipital tRNS
tRNS applied to occipital brain regions
Frontal tRNS
tRNS applied to frontal brain regions
Sham/placebo tACS
tACS is activated only for 30 seconds and then turned off, thus resulting ineffective
Sham/placebo tRNS
tRNS is activated only for 30 seconds and then turned off, thus resulting ineffective
Locations (1)
Università Vita-Salute San Raffaele
Milan, Italy