Clinical Research Directory

Inclusion Criteria: 1. Risk factors for chronic obstructive pulmonary disease. Having one item from a, b, and c (risk factors will be further optimized based on the screening results of high-risk populations): 1. smoking history (including previous and current smokers); 2. 1 year or more of exposure to dust or chemical toxins; 3. Indoor air pollution for 1 year or more (use of contaminated fuels, passive smoking, exposure) Oil fumes, etc. 2. Have a history of chronic bronchitis and/or emphysema, and have one of the following chronic respiratory symptoms: 1. Cough (more than 3 months per year, continuous for 2 years or more); 2. Coughing phlegm (more than 3 months per year, continuous for 2 years or more); 3. Difficulty breathing (more than 3 months per year, continuous for 2 years or more). 3. The lung function test meets the following criteria: forced expiratory volume in one second (FEV1)/forced vital capacity (FVC) ≥ 70% and FEV1 accounting for%\<80% of the expected value. 4. Meets the diagnostic criteria for lung qi deficiency syndrome. 5. Age range from 18 to 80 years old. 6. Voluntarily participate in the study and sign an informed consent form. Exclusion Criteria: * Pregnant and planned pregnancy, lactating women. * Dementia and various mental illness patients. * Other diseases with chronic cough, sputum production, or difficulty breathing. * Merge tumors. * Merge severe cardiovascular and cerebrovascular diseases. * Concomitant severe liver and kidney diseases. * Participants in clinical trials of other drugs. * Allergies to intervention drugs.