Clinical Research Directory

Inclusion Criteria: * Complaints of peripheral neuropathy among patients who have completed the standard chemotherapy treatment protocol due to colorectal cancer, entered the follow-up process and come to the outpatient clinic for routine control. * Registered to Selçuk University Faculty of Medicine Hospital Medical Oncology Polyclinic * Karnofsky Performance Scale must be 80 or above * Over 25 years old, under 65 years old * Presence of grade 2 or higher peripheral neuropathy, * Being conscious and cooperative * Verbal and written approval to participate in the study after an explanation about the study is made. Exclusion Criteria: * Having any skin sensitivity on hands and feet before * Refused to participate in the study after making a statement about the study * Development of peripheral neuropathy due to reasons other than chemotherapy \[tumor compression, nutritional disorders, infections or major systemic disease (diabetes mellitus, etc.)\] * Bone or spine metastases