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NOT YET RECRUITING
NCT06376942
PHASE2/PHASE3

A RCT to Compare the Effectiveness of Nebulized Anticholinergics for Cough Suppression During Flexible Bronchoscopy

Sponsor: Post Graduate Institute of Medical Education and Research, Chandigarh

View on ClinicalTrials.gov

Summary

No study has examined the role of inhaled glycopyrrolate on mucus secretion. We hypothesize that nebulized glycopyrrolate will improve bronchoscopy procedure by effectively suppressing airway mucus secretion, thereby decreasing cough, and thus improving patient comfort during bronchoscopy. In this study, we aim to compare the efficacy of nebulized glycopyrrolate versus nebulized ipratropium in suppression of cough during flexible bronchoscopy.

Official title: A Randomized, Double-blind, Placebo-controlled Trial to Compare the Effectiveness of Nebulized Anticholinergics for Cough Suppression During Flexible Bronchoscopy

Key Details

Gender

All

Age Range

18 Years - 85 Years

Study Type

INTERVENTIONAL

Enrollment

1050

Start Date

2024-04-24

Completion Date

2025-06-15

Last Updated

2024-04-22

Healthy Volunteers

No

Interventions

DRUG

Glycopyrronium

Nebulized glycopyrronium 50 mcg

DRUG

Ipratropium

Nebulized iptratropium 500 mcg

OTHER

Saline

0.9% saline 2 ml

Locations (1)

Bronchoscopy suite, PGIMER

Chandigarh, India