Clinical Research Directory

Inclusion Criteria: * Age: ≥ 18 years. * Good general health. * Single-tooth implant treatment. Presence of adjacent teeth and opposing occluding teeth (for measurement stent indexing). * Incisors, canines and premolars. * Presence of three intact socket walls after tooth extraction with a defect of more than 50% loss of the buccal ridge wall and no fragment of root should be left. * Reasons for tooth extraction: carious lesion, endodontic complication, root fracture and prosthetic reason. * Good oral and periodontal health. * Full-mouth plaque and bleeding \< 20%. * Able and willing to follow study procedures and instructions. * Informed consent. Exclusion Criteria: * ≤ 18 years. * Comprised health. Existence of any systemic condition such as uncontrolled diabetes mellitus, cancer, HIV, disorders that compromise wound healing, chronic high dose steroid therapy, intravenous and oral bisphosphonate therapy, bone metabolic diseases, history of irradiation of the head and neck area, or any other immunosuppressive therapy that would contraindicate oral surgical treatment. * Absence of any adjacent teeth or the opposing occluding teeth. * Molars. * More than one bone wall defect. * Sinus pathology. * Allergy or hypersensitivity to medications or any of the products used throughout the study. * Heavy smokers (defined as \>10 cigarettes per day or \>1 cigar per day) or chew tobacco, including within 3 months prior to enrollment. * Untreated periodontitis. * Periapical or periodontal infection. * Full-mouth plaque and bleeding \> 20%. * No informed consent