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PPOS vs GnRH Antagonist in Ovarian Stimulation (ProGanOS Study)
Sponsor: Mỹ Đức Hospital
Summary
This non-inferiority randomized controlled trial will be conducted at My Duc Hospital, Ho Chi Minh City, Vietnam. This study compares the effectiveness of Progestin-Primed Ovarian stimulation versus GnRH protocol for ovarian stimulation in IVF treatment. Participants will be randomly assigned in a 1:1 ratio to receive Progestins or GnRH antagonists.
Official title: Effectiveness of Progestin-Primed Ovarian Stimulation Versus GnRH Antagonist Protocol for Ovarian Stimulation in IVF: a Randomized Clinical Trial
Key Details
Gender
FEMALE
Age Range
18 Years - 40 Years
Study Type
INTERVENTIONAL
Enrollment
626
Start Date
2024-04-24
Completion Date
2026-09-30
Last Updated
2026-03-20
Healthy Volunteers
No
Conditions
Interventions
Dydrogesterone 10 mg
Dydrogesterone 10mg orally 2 times daily, starting on the day of gonadotropin injection to the oocyte maturation trigger night.
Cetrorelix 0.25 mg
Cetrorelix 0.25mg is injected subcutaneously once a day. It is given from day 5 or day 6 of stimulation by the oocyte maturation trigger day.
Locations (1)
My Duc Hospital
Ho Chi Minh City, Ho Chi Minh City, Vietnam