Clinical Research Directory

Inclusion Criteria: Healthy volunteers requiring one single implant or partial implant-supported rehabilitation in an edentulous area of the posterior mandible or maxilla Exclusion Criteria: * Patients unable to commit to follow-up * General contraindications to implant surgery * Immuno-suppressed/immune-compromised patients * Patients irradiated in the head and/or neck * Uncontrolled diabetes * Pregnancy, childbearing potential, breastfeeding * Smoking habit * Untreated periodontal disease (Caton et al, J Clin Periodontol 2018) * Poor oral hygiene and motivation (plaque index \> 20%) * Addiction to alcohol or drugs * Psychiatric problems and/or unrealistic expectations * Patients with an acute infection (abscess) or suppuration in the site intended for implant placement * Patients treated or under treatment with intravenous amino-bisphosphonates * Patients referred only for implant placement if the follow-up cannot be done at the treatment center * Patients participating in other studies, if the present protocol could not be fully adhered to * Patients with allergy/hypersensitivity to penicillin or drug excipients * Patients recently treated with antibiotics for other indications