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RECRUITING
NCT06379360
PHASE2

Maintenance Therapy of Hypomethylating Agent (HMA) in Favorable Risk Acute Myeloid Leukemia (AML) Patients

Sponsor: The First Affiliated Hospital of Soochow University

View on ClinicalTrials.gov

Summary

HMA maintenance therapy is expected to benefit overall survival (OS) and relapse free survival (RFS) in AML patients with favorable risk.

Official title: Maintenance Therapy of Hypomethylating Agent (HMA) in Favorable Risk Acute Myeloid Leukemia (AML) Patients: A Single Arm, Multi Center Clinical Trial

Key Details

Gender

All

Age Range

16 Years - Any

Study Type

INTERVENTIONAL

Enrollment

77

Start Date

2020-11-01

Completion Date

2028-12-31

Last Updated

2026-03-19

Healthy Volunteers

No

Interventions

DRUG

Hypomethylating agent, Azacitidine or Decitabine

All enrolled patients received maintenance therapy consisting of Azacitidine (75mg/m2, subcutaneous injection, days 1-7) or Decitabine (20mg/m2, intravenous infusion, days 1-5), every three months as a cycle, for a maintenance therapy of 4-8 cycles.

Locations (1)

The First Affiliated Hospital of Soochow University

Suzhou, Jiangsu, China