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Burn Study- Tranexamic Acid Versus Thrombin in Split Thickness Skin Graft
Sponsor: University of Kansas Medical Center
Summary
Investigators hypothesize that topical tranexamic acid will have better or comparable efficacy to topical thrombin in reducing hematoma formation at the wound base. The purpose of the study is to demonstrate that topical tranexamic acid will be a non-inferior alternative medication to the current standard of care,THROMBIN-JMI® , and at a lower cost to the health system.
Official title: The Use of Topical Tranexamic Acid Versus Thrombin Spray for the Management of Split Thickness Skin Graft Recipient Site in Burn Management
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
62
Start Date
2024-07-11
Completion Date
2026-12
Last Updated
2025-10-20
Healthy Volunteers
No
Conditions
Interventions
Tranexamic acid
100mg/mL 10mL vials x2 of injectable tranexamic acid will be filled into a 20 milliliter syringe with a spray tip.
Thrombin JMI
The wound base is then sprayed with a film of Thrombin-JMI
skin graft
Skin is taken from uninjured part of the participant's body and used to surgically cover a wound or injured area with skin that contains the epidermis and a portion of the dermis.
Locations (1)
The University of Kansas Health System
Kansas City, Kansas, United States