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COMPLETED
NCT06381245

First-time Ablation of Atrial Fibrillation Registry

Sponsor: Medical University of Warsaw

View on ClinicalTrials.gov

Summary

Atrial fibrillation (AF) is a prevalent cardiac arrhythmia affecting millions globally, with projections indicating a doubling of cases by 2050. AF is linked to heightened cardiovascular risks like stroke and increased healthcare costs. Ablation, targeting the arrhythmia substrate, is a method to manage AF, yet recurrence rates remain high (20-45% in the first year). Studies highlight the impact of comorbidities, AF characteristics, ablation techniques, and myocardial remodeling markers on AF progression and ablation efficacy. However, there's no definitive guidance on selecting these factors for predicting treatment success. The aim of this study is to investigate predictors of successful AF ablation in the following areas: (a) clinical factors, (b) electrophysiological, (c) electrocardiographic, (d) ultrasound, (e) cardiac anatomy, (f) biomarkers.

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

340

Start Date

2023-12-01

Completion Date

2026-04-30

Last Updated

2026-06-23

Healthy Volunteers

Not specified

Interventions

DIAGNOSTIC_TEST

PPG-based remote heart rhythm/rate monitoring

PPG-based remote heart rhythm/rate monitoring

DIAGNOSTIC_TEST

ECG-based remote heart rhythm/rate monitoring

ECG-based remote heart rhythm/rate monitoring

DIAGNOSTIC_TEST

Transthoracic and transesophageal echocardiography examination

Transthoracic and transesophageal echocardiography examination

DIAGNOSTIC_TEST

Liver ultrasound examination

Liver ultrasound examination

DIAGNOSTIC_TEST

Rotational angiography with three-dimensional reconstruction

Rotational angiography with three-dimensional reconstruction

DIAGNOSTIC_TEST

Blood-derived biomarker analysis

Blood-derived biomarker analysis

DIAGNOSTIC_TEST

Mobile health-based spirometry

Mobile health-based spirometry

Locations (1)

Medical University of Warsaw

Warsaw, Poland