Clinical Research Directory
Browse clinical research sites, groups, and studies.
The Project of Gestational Hypertension and Preeclampsia Screening and Prevention Center
Sponsor: The Third Affiliated Hospital of Guangzhou Medical University
Summary
Preeclampsia is the main cause of illness and death in pregnant women and fetuses. Currently, there is no effective treatment for preeclampsia in clinical practice, and the fundamental treatment is still termination of pregnancy and placental delivery. Therefore, early prediction of preeclampsia and targeted strengthening of high-risk pregnant women supervision, early intervention and diagnosis and treatment can greatly reduce the serious obstetric complications and perinatal maternal and fetal deaths caused by preeclampsia, which has significant social and clinical significance.
Official title: The Project of Gestational Hypertension and Preeclampsia Screening and Prevention
Key Details
Gender
FEMALE
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
50000
Start Date
2023-08-01
Completion Date
2028-12-31
Last Updated
2024-09-19
Healthy Volunteers
Yes
Conditions
Interventions
Screening method
All pregnant women in the group were screened for pre-eclampsia risk according to the clinical risk factors listed in NICE Guidelines (2019).
Screening method
In the first trimester, pregnant women with routine MAP and PLGF (with UtA-PI detection conditions plus UtA-PI) were tested, and the risk of preeclampsia was evaluated based on Bayes rule combined with maternal factors. In the second and third trimester of pregnancy, routine determination of PLGF or sFlt-1/PLGF was used to evaluate the risk of preeclampsia.
Locations (1)
FANG HE
Guangzhou, Guangdong, China