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Topical TRanexamic Acid Vs. Placebo on Acute Postoperative Pain Following DRF Fixation
Sponsor: University Health Network, Toronto
Summary
The goal of this study is to find out whether the use of topical tranexamic acid (TXA) into the surgical wound will result in less post-operative pain, less pain killer use, and better post-operative use of the wrist in people undergoing surgery for a wrist fracture compared to not using topical TXA (placebo).
Official title: The Effect of Topical TRanexamic Acid Vs. Placebo on Acute Postoperative Pain Following Distal Radius Fracture Fixation: a Randomized Controlled Trial - the TRADR Study
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
90
Start Date
2025-03
Completion Date
2026-09
Last Updated
2025-03-28
Healthy Volunteers
No
Conditions
Interventions
Topical TRanexamic Acid
10mL of 100mg/mL TXA will be administered into the surgical wound prior closure.
Placebo
10mL of 100mg/mL normal saline will be administered into the surgical wound prior closure.
Locations (1)
Toronto Western Hospital
Toronto, Ontario, Canada