Clinical Research Directory

Inclusion Criteria: * Individuals of both genders. * Must be in good physical health. * Age between 20 and 65 years. * Presence of both static (unchanging) and moderate dynamic (movement-induced) wrinkles on the forehead or glabellar region. * Must possess the willingness and ability to understand and provide informed consent, as well as effectively communicate with study personnel. Exclusion Criteria: * Pregnant or breastfeeding female. * Age below 20 or above 65 years. * History of neuromuscular disorders, such as myasthenia gravis. * History of facial surgery or presence of scars in the treatment area that could potentially interfere with or confound the results of the study. * Recent treatment history within the past 6 months in the forehead or glabellar region, including: * Ablative laser procedures. * Radiofrequency device treatments. * Ultrasound device treatments. * Medium to deep chemical peels. * Temporary soft tissue augmentation. * Semi-permanent soft tissue augmentation within the past 2 years. * Permanent soft tissue augmentation. * Planned cosmetic procedures within the next 6 months in the same region. * Intended use of tretinoin or retinoic acid within the next 6 months. * Presence of active infection in the treated area, excluding mild acne. * Allergy to cow's milk protein or albumin. * Use of aminoglycoside medications. * Current use of anticoagulation therapy. * History of bleeding disorders. * Diagnosis of mental illness. * Inability to comprehend the study protocol or provide informed consent.