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Personalized GI Motility Responses to Diet
Sponsor: University of Illinois at Urbana-Champaign
Summary
The goal of this randomized, crossover, clinical trial is to link: 1) gastrointestinal motility patterns induced by acute consumption of whole and refined grains, 2) enteric microbial production of bioactive metabolites, and 3) circulating postprandial appearance of metabolites important to cardiometabolic health including glucose, triglycerides, and cholesterol. Participants will be asked to consume a Smartpill monitoring device that records metrics of gastrointestinal motility in response to whole or refined grains, monitor cardiometabolic metabolties over an 8 hour postprandial window, and provide a fecal sample for microbiome-related analyses.
Official title: Personalized Gastrointestinal Motility Responses to Dietary Fiber and Gut Microbial Metabolites
Key Details
Gender
All
Age Range
21 Years - 63 Years
Study Type
INTERVENTIONAL
Enrollment
50
Start Date
2024-03-07
Completion Date
2025-06-02
Last Updated
2024-04-26
Healthy Volunteers
Yes
Conditions
Interventions
Whole grain rye bread
Single consumption of 4.3 oz of whole grain rye bread
Refined grain rye bread
Single consumption of 4.3 oz of refined grain rye bread
Locations (1)
University of Illinois at Urbana-Champaign
Urbana, Illinois, United States