Clinical Research Directory
Browse clinical research sites, groups, and studies.
Characterizing Diversity and Antifungal Resistance in Immunocompromised ICU Patients With Respiratory Tract Infections
Sponsor: New Valley University
Summary
Immunocompromised individuals face a heightened risk of life-threatening fungal infections, which arise from a multitude of environmental and commensal fungi. Surveillance data from ICUs worldwide identifies Candida spp. as the dominant foe, responsible for 80% of such infections, earning it the dubious distinction of being the third most prevalent pathogen. While C. albicans holds the dubious crown as the most common Candida offender, recent years have witnessed a concerning trend toward non-Albicans candida, raising concerns about potential antifungal resistance.
Official title: Unveiling the Fungal Frontier: Characterizing Diversity and Antifungal Resistance in Immunocompromised ICU Patients With Respiratory Tract Infections
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
250
Start Date
2025-12-01
Completion Date
2027-06-01
Last Updated
2025-08-14
Healthy Volunteers
No
Interventions
Complete blood count
blood sample
C-reactive protein, urea, creatinine, Random blood glucose (RBG), aspartate aminotransferase (AST), alanine aminotransferase (ALT)
serum sample
CT chest
Computed tomography of the chest
Microscopic examination
sputum and bronchoalveolar lavage (BAL)
culture and sensitivity
for bacterial and fungal