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Effects of Tomato Consumption on Steatosis, Intestinal Function and Glucose and Lipid Metabolism in Subjects With NAFLD
Sponsor: Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis
Summary
The study in question is an interventional study with nutritional intervention. the aim of the study is to evaluate whether a diet enriched with tomatoes can have favorable effects on: * specific aspects associated with NAFLD, such as the degree of hepatic steatosis and fibrosis; * circulating levels of molecules correlated with the degree of generalized and hepatic inflammation and the blood concentrations of metabolic and cardiovascular risk factors associated with abdominal obesity; * intestinal barrier; * body composition; * intestinal microbiota; * symptoms of IBS (irritable bowel syndrome) in patients with NAFLD.
Official title: Evaluation of the Effects of Tomato Consumption on the Parameters of Hepatic Steatosis, Intestinal Function and on Glucose and Lipid Metabolism in Subjects With NAFLD
Key Details
Gender
All
Age Range
18 Years - 75 Years
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2024-05-14
Completion Date
2025-05-20
Last Updated
2024-09-04
Healthy Volunteers
Yes
Interventions
Experimental: Case Group - Tomato-free diet
Nutritional intervention without tomatoes and sauce
Experimental: Case group - Diet enriched with tomatoes
Nutritional intervention enriched with tomatoes and souce
Locations (1)
Irccs Saverio de Bellis
Castellana Grotte, BARI, Italy