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RECRUITING
NCT06389851
NA

Effects of Tomato Consumption on Steatosis, Intestinal Function and Glucose and Lipid Metabolism in Subjects With NAFLD

Sponsor: Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis

View on ClinicalTrials.gov

Summary

The study in question is an interventional study with nutritional intervention. the aim of the study is to evaluate whether a diet enriched with tomatoes can have favorable effects on: * specific aspects associated with NAFLD, such as the degree of hepatic steatosis and fibrosis; * circulating levels of molecules correlated with the degree of generalized and hepatic inflammation and the blood concentrations of metabolic and cardiovascular risk factors associated with abdominal obesity; * intestinal barrier; * body composition; * intestinal microbiota; * symptoms of IBS (irritable bowel syndrome) in patients with NAFLD.

Official title: Evaluation of the Effects of Tomato Consumption on the Parameters of Hepatic Steatosis, Intestinal Function and on Glucose and Lipid Metabolism in Subjects With NAFLD

Key Details

Gender

All

Age Range

18 Years - 75 Years

Study Type

INTERVENTIONAL

Enrollment

60

Start Date

2024-05-14

Completion Date

2025-05-20

Last Updated

2024-09-04

Healthy Volunteers

Yes

Conditions

Interventions

DIETARY_SUPPLEMENT

Experimental: Case Group - Tomato-free diet

Nutritional intervention without tomatoes and sauce

DIETARY_SUPPLEMENT

Experimental: Case group - Diet enriched with tomatoes

Nutritional intervention enriched with tomatoes and souce

Locations (1)

Irccs Saverio de Bellis

Castellana Grotte, BARI, Italy