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Passive Leg Raise and Mini-fluid Challenge Effect on Various Cardiac Output Surrogates for Fluid Responsiveness
Sponsor: CentraCare
Summary
In the critically ill population, fluid administration in an unstable patient is perhaps the most common intervention that is performed. Uncorrected hypovolemia with inappropriate vasopressors lead to organ hypoperfusion where as overzealous fluid administration especially in ARDS (Adult respiratory distress syndrome) can increase mortality. It has been estimated that only 50% of hemodynamically unstable critically ill patients are volume responsive, hence dynamic assessment of preload responsiveness has been proposed to better identify those individuals who would benefit from fluid bolus.
Official title: Passive Leg Raise and Mini-fluid Challenge Effect on Various Cardiac Output Surrogates Such as Pulse Pressure Variation (PPV), End-tidal CO2 (Carbon Dioxide), Bioreactance (Stroke Volume Index -SVI) and Velocity Time Integral on Echocardiographic Exam for Fluid Responsiveness in Patients With Moderately Severe ARDS (Acute Respiratory Distress Syndrome)
Key Details
Gender
All
Age Range
30 Years - 90 Years
Study Type
OBSERVATIONAL
Enrollment
64
Start Date
2023-07-01
Completion Date
2025-06
Last Updated
2024-08-22
Healthy Volunteers
No
Conditions
Interventions
Passive leg raise, SVI via bioreactance, Echo based VTI
No interventions other than fluid challenge
Locations (1)
St Cloud Hospital
Saint Cloud, Minnesota, United States