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RECRUITING
NCT06390423

Passive Leg Raise and Mini-fluid Challenge Effect on Various Cardiac Output Surrogates for Fluid Responsiveness

Sponsor: CentraCare

View on ClinicalTrials.gov

Summary

In the critically ill population, fluid administration in an unstable patient is perhaps the most common intervention that is performed. Uncorrected hypovolemia with inappropriate vasopressors lead to organ hypoperfusion where as overzealous fluid administration especially in ARDS (Adult respiratory distress syndrome) can increase mortality. It has been estimated that only 50% of hemodynamically unstable critically ill patients are volume responsive, hence dynamic assessment of preload responsiveness has been proposed to better identify those individuals who would benefit from fluid bolus.

Official title: Passive Leg Raise and Mini-fluid Challenge Effect on Various Cardiac Output Surrogates Such as Pulse Pressure Variation (PPV), End-tidal CO2 (Carbon Dioxide), Bioreactance (Stroke Volume Index -SVI) and Velocity Time Integral on Echocardiographic Exam for Fluid Responsiveness in Patients With Moderately Severe ARDS (Acute Respiratory Distress Syndrome)

Key Details

Gender

All

Age Range

30 Years - 90 Years

Study Type

OBSERVATIONAL

Enrollment

64

Start Date

2023-07-01

Completion Date

2025-06

Last Updated

2024-08-22

Healthy Volunteers

No

Interventions

DIAGNOSTIC_TEST

Passive leg raise, SVI via bioreactance, Echo based VTI

No interventions other than fluid challenge

Locations (1)

St Cloud Hospital

Saint Cloud, Minnesota, United States