Clinical Research Directory

Inclusion Criteria: * Confirmed diagnosis of autosomal recessive LGMD2A (two pathogenic mutations in the calpain 3 gene) * Ability to participate in the tests and examinations planned by the study (manual muscle tests, motor scales) * Informed and having signed a consent form * Affiliate to a social security scheme in France (beneficiary or entitled person). Exclusion Criteria: * Patient with another disease likely to significantly interfere with the interpretation of the natural history of LGMD2A * Participant in a clinical trial with an investigational product within 3 months preceding inclusion * Patient unable or unwilling to comply with protocol requirements * Patient under guardianship, curatorship or legal protection * Pregnant or breastfeeding woman * Patient deprived of liberty * Adult patient unable to express consent * Refusal to participate