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ACTIVE NOT RECRUITING
NCT06392126
PHASE1/PHASE2

Personalized Antisense Oligonucleotide Therapy for A Single Participant With CHCHD10 ALS

Sponsor: n-Lorem Foundation

View on ClinicalTrials.gov

Summary

This research project entails delivery of a personalized antisense oligonucleotide (ASO) drug designed for a single participant with amyotrophic lateral sclerosis (ALS) due to a pathogenic variant in CHCHD10

Official title: An Open-label Study of an Experimental Antisense Oligonucleotide Treatment for a Single Participant With Amyotrophic Lateral Sclerosis (ALS) Due to a Pathogenic Variant in CHCHD10

Key Details

Gender

MALE

Age Range

48 Years - Any

Study Type

INTERVENTIONAL

Enrollment

1

Start Date

2024-04-16

Completion Date

2026-04

Last Updated

2025-08-05

Healthy Volunteers

No

Interventions

DRUG

nL-CHCHD-001

Personalized antisense oligonucleotide

Locations (1)

Mayo Clinic

Jacksonville, Florida, United States