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Evaluation of Salivary RNA in Subjects Scheduled for Surgery for a Gynecologic Pathology
Sponsor: ZIWIG
Summary
GynRAN is an international, multicentre, transversal, diagnostic and non-interventional study carried out in gynecology-obstetrics/gynecological oncology departments that aims to identify a diagnostic signature for gynecological pathologies by analyzing of coding and non-coding RNA contained in patients saliva. The study population consists of patients with clinically symptomatic females with one or more of the gynecological pathologies (endometriosis, adenomyosis, ovarian cysts, fibroids, ovarian/cervical/uterine cancer) and asymptomatic females. The patients concerned by the study will be managed without modification of the care pathway, nor modification of the therapeutic indications, nor modification of the diagnostic or follow-up examinations necessary according to the context, which are carried out according to the local recommendations.
Key Details
Gender
FEMALE
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
2500
Start Date
2024-12-05
Completion Date
2026-12
Last Updated
2025-01-23
Healthy Volunteers
Yes
Conditions
Interventions
Saliva sample
Saliva sample
Locations (13)
CHU d'Angers
Angers, France
Clinique Tivoli Ducos - IFEMENDO
Bordeaux, France
Institut Bergonié
Bordeaux, France
CHU Caen
Caen, France
CGFL
Dijon, France
CHU Lyon Sud
Lyon, France
American Hospital of Paris
Neuilly-sur-Seine, France
CHU de Rennes Site Hôpital Sud
Rennes, France
Clinique La sagesse
Rennes, France
CHU Rouen
Rouen, France
Clinique Pasteur
Toulouse, France
CHU Bretonneau-Tours
Tours, France
Institut Gustave Roussy
Villejuif, France