Clinical Research Directory

Inclusion Criteria: 1. The patient with upper gastrointestinal hemorrhage age ≥ 18 years old 2. The patient with gastroduodenal ulcer with indication for hemostatic intervention including 2.1 Forrest classification 1a (Active spurting) 2.2 Forrest classification 1b (Active oozing) 2.3 Forrest classification 2a (Non-bleeding visible vessel; NBVV) 2.4 Forrest classification 2b (Adherent clot) with lesion underneath clot which need hemostatic intervention including active spurting, active oozing or non-bleeding visible vessel Exclusion Criteria: 1. Uncorrectable hemostasis laboratory including serum platelet \< 50000 /mm3 or International Normalized Ratio (INR) \>1.5 2. Bleeding from cancerous gastroduodenal ulcer 3. The patient with history of gastric surgery 4. The patient with history of bleeding gastroduodenal ulcer within 30 days prior to enrollment 5. The patient with history of proton pump inhibitor allergy 6. Pregnant 7. The patient deny to participate in the study