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Circulating Microvesicles Regulating Metabolic Homeostasis in Obesity After Caloric Restriction Programs
Sponsor: Institut Investigacio Sanitaria Pere Virgili
Summary
The main aim of the present study is to evaluate the effectiveness of two dietary protocols: Daily Caloric Restriction (DCR) and Early Time-Restricted Feeding + DCR (eTRE) on metabolic homeostasis and the influence of circulating extracellular vesicles (EVs) as inter-organ communication elements in obese patients.
Official title: The Usefulness of Circulating Microvesicles (host and Bacterial) in Regulating Metabolic Homeostasis in Obesity Randomized Study of Parallel Arms in Obese Patients Undergoing Caloric Restriction Diet Vs. Early Time-restricted Eating
Key Details
Gender
All
Age Range
18 Years - 70 Years
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2024-05-20
Completion Date
2025-12-20
Last Updated
2024-10-04
Healthy Volunteers
Yes
Conditions
Interventions
Active Comparator: Continuous calorie restriction
Individualized continuous calorie restriction diet based on healthy Mediterranean diet recommendations aiming to achieve at least a 5% weight loss at the end of the intervention
eTRE
early (morning) time-restricted eating pluss individualized continuous calorie restriction diet based on healthy Mediterranean diet recommendations aiming to achieve at least a 5% weight loss at the end of the intervention
Locations (1)
Hospital Universitario de Tarragona Juan XXIII
Tarragona, Tarragona, Spain