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Research on Intelligent Screening and Decision-making for Neoadjuvant Therapy in Locally Advanced Gastric Cancer Based on Multi-omics Integration
Sponsor: Zhejiang University
Summary
In this study, investigators utilize a radiopathomics integrated Artificial Intelligence (AI) supportive system to predict tumor response to neoadjuvant chemoradiotherapy (nCRT) before its administration for patients with locally advanced gastric cancer (LAGC). By the system, the postoperative tumor regression grade (TRG) of the participants will be identified based on the radiopathomics features extracted from the pre-nCRT Enhanced CT and biopsy images. The ability to predict TRG will be validated in this multicenter, prospective clinical study.
Key Details
Gender
All
Age Range
18 Years - 75 Years
Study Type
OBSERVATIONAL
Enrollment
120
Start Date
2024-07-01
Completion Date
2025-12-01
Last Updated
2024-05-02
Healthy Volunteers
No
Conditions
Locations (4)
Gastrointestinal Department of First Affiliated Hospital of Zhejiang University
Hanzhou, Zhejiang, China
Gastrointestinal Department of Second Affiliated Hospital of Zhejiang University
Hanzhou, Zhejiang, China
Gastrointestinal Department of Zhejiang Cancer Hospital
Hanzhou, Zhejiang, China
Shaoxing Shangyu People's Hospital
Shaoxing, Zhejiang, China