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NOT YET RECRUITING
NCT06397807

Postoperative Pain Management on Patients Undergoing Lung Tumor Resection

Sponsor: China Medical University Hospital

View on ClinicalTrials.gov

Summary

Multimodal analgesia (MMA) is an essential part of Enhanced Recovery After Surgery (ERAS) protocol. The principle of MMA is to manage pain with analgesics of multiple classes acting on distinct target sites through different strategies. MMA can reduce the adverse reaction caused by opioids and improve the quality of recovery from surgery. Inadequate postoperative pain management will increase the risk of complications, including pneumonia, deep vein thrombosis, infection, delayed surgical healing, and chronic postoperative pain.

Official title: Postoperative Pain Management on Patients Undergoing Video-assisted Thoracoscopic (VATS) Lung Tumor Resection: a Prospective Cohort Study

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

400

Start Date

2024-05-31

Completion Date

2026-05-30

Last Updated

2024-05-03

Healthy Volunteers

No

Interventions

DRUG

Dinalbuphine sebacate

Dinalbuphine sebacate (DS) is a long-acting injectable. With oil-based formulation, DS will slowly releases to blood vessel and be hydrolyzed to nalbuphine after intramuscularly injection. The analgesic effect lasts around 5 to 7 days.

DRUG

Analgesic injectables

Opioids, NSAIDs or acetamol will be administrated as need.

DRUG

Enteral analgesics

Opioids, NSAIDs or acetaminophen will be prescribed if necessary.