Clinical Research Directory

Inclusion Criteria for patients with unilateral carotid artery stenosis: * Men and Women aged ≥ 18 years * Signed informed consent * Normal ophthalmic findings, unless the investigator considers an abnormality to be clinically irrelevant * Diagnosis of unilateral carotid artery stenosis and scheduled carotid endarterectomy or carotid artery stenting Inclusion criteria for healthy age- and sex-matched control subjects: * Men and Women aged ≥ 18 years * Signed informed consent * Normal ophthalmic findings, unless the investigator considers an abnormality to be clinically irrelevant * Normal findings in the medical history, unless the investigator considers an abnormality to be clinically irrelevant * Non-Smokers Exclusion criteria for patients with carotid artery stenosis and healthy age- and sex-matched control subjects: * Blood donation in the three weeks preceding the study * Symptoms of a clinically relevant illness in the three weeks preceding the study * Ocular inflammation or infection within the last 3 months * History of family history of epilepsy * Diabetes mellitus type 1 or type 2 * Pregnant or breast-feeding women * Women of childbearing potential (neither menopausal, nor hysterectomized, nor sterilized) not using effective contraception