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Surgical Prehabilitation on Autonomic Nervous System (TUNE)
Sponsor: Università Vita-Salute San Raffaele
Summary
This study will be a multicenter interventional randomized trial evaluating the effect of a multimodal prehabilitation program on heart rate variability (HRV). In the same protocol the impact of HRV on hospital length of stay will be identified. One hundred patients aged 18 years or older scheduled for elective surgery will be eligible for enrolment, if they will not present any exclusion criteria. Patients will be randomized with a 1:1 allocation to receive either prehabilitation or standard of care.
Official title: The Effect of Surgical Prehabilitation on Autonomic Nervous System Regulation
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
100
Start Date
2024-07-29
Completion Date
2025-10
Last Updated
2025-08-06
Healthy Volunteers
No
Conditions
Interventions
Multimodal prehabilitation Program
A tailored intervention will be prescribed if specific physical, nutritional or psychological impairments will be identified during the assessment phase. Based on the data obtained during the multimodal assessment, different domains and levels of care will be prescribed, focusing on exercise training, and/or nutrition optimization, and/or distress-coping techniques. Different combinations of three domains will be utilized to maximize their synergistic anabolic effect. The duration of program will be set at 4 weeks. All activities will be performed in dedicated suites at each site, under supervision of qualified health professionals.
Locations (2)
IRCCS San Raffaele Scientific Institute
Milan, Italy
Università degli studi di Verona
Verona, Italy