Clinical Research Directory

Inclusion Criteria: * Age ≥18 years * ECOG 0-2 * Histological diagnosis of squamous carcinoma and/or adenocarcinoma of the uterine cervix * FIGO IB2 Stadium - IVA (staging 20018) * No contraindications to performing MRI of the pelvis * Informed consent Exclusion Criteria: * Age \<18 years * PS \>2 * Previous cancer in the last 10 years * Previous radiation treatment in the region of interest * Presence of pathologies that contraindicate radiotherapy treatment (genetic syndromes of hyper-radiosensitivity, ulcerative colitis, diverticulitis in the acute phase, severe diverticulosis, chronic pelvic inflammation) * Presence of internal diseases that contraindicate chemotherapy or radio-chemotherapy treatment (severe liver disease, heart disease, renal failure, etc.) * Presence of distant metastases in sites other than the pelvic lymph nodes * Any significant medical condition that in the opinion of the investigator may interfere with the patient's optimal participation in the study