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COMPLETED
NCT06401928
NA

Electrical Brain Stimulation for Treatment of Secondary Symptoms in Multiple Sclerosis

Sponsor: The National Brain Mapping Laboratory (NBML)

View on ClinicalTrials.gov

Summary

Multiple Sclerosis (MS) is an autoimmune disease associated with physical disability, psychological impairment, and cognitive dysfunction. As a result, the disease burden is high, and treatment options are limited. In this randomized, double-blind study, the investigators planned to use repeated electrical stimulation and assess mental health-related variables (e.g., quality of life, sleep, psychological distress) and cognitive dysfunction in patients with MS.

Official title: Electrical Brain Stimulation for Improving Mental Health and Cognitive Functioning in Patients With Multiple Sclerosis

Key Details

Gender

All

Age Range

18 Years - 60 Years

Study Type

INTERVENTIONAL

Enrollment

53

Start Date

2023-02-28

Completion Date

2024-01-31

Last Updated

2026-08-05

Healthy Volunteers

No

Interventions

DEVICE

transcranial direct current stimulation

Patients will receive 10 sessions of either 1.5 mA electrical stimulation for 20 minutes each day over 10 consecutive days.

DEVICE

transcranial direct current stimulation combined with cognitive training

Patients will receive 10 sessions of 20 minutes of 1.5 mA electrical stimulation on 10 consecutive days. Each session is followed by 30 minutes cognitive training in which patients conduct several computerized cognitive tests.

DEVICE

transcranial direct current stimulation

Patients will receive 10 sessions of sham (placebo) electrical stimulation for 20 minutes each day over 10 consecutive days.

Locations (1)

Multiple Sclerosis Association of Guilan

Rasht, Giulan, Iran