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Left Atrial Appendage Arrhythmogenic and Thrombogenic Substrate
Sponsor: University Hospital Bispebjerg and Frederiksberg
Summary
The purpose of the project is to elucidate whether it is possible to identify which patients are at risk of forming blood clots that can cause stroke based on analysis of the electrocardiogram. In connection with the operation, the small pouch known as the auricle of the heart is closed, which can be completely removed after closing. This procedure is common in patients with atrial fibrillation to protect the brain from stroke. In the project, all patients will have this auricle closed if they agree to participate in the project. After closure, the auricle is usually discarded. We will analyze the blood and the auricle tissue taken (if available) in connection with the operation itself, together with the analysis of the electrocardiogram recorded before the planned heart operation.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
1000
Start Date
2024-08-01
Completion Date
2035-12-31
Last Updated
2026-01-15
Healthy Volunteers
No
Conditions
Interventions
left atrial appendage closure
systematic closure of the left atrial appendage in addition to the planned heart surgery
Locations (1)
Rigshospitalet
Copenhagen, Denmark