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NOT YET RECRUITING
NCT06406686
NA

Ablation Index in Standard vs. High Power Radiofrequency Ablation for Typical Atrial Flutter: A Randomized Study (AITAF)

Sponsor: University of Calgary

View on ClinicalTrials.gov

Summary

A randomized controlled trial will be conducted to evaluate the efficacy of Ablation Index-guided high power - short duration (HPSD) ablation compared to conventional power settings in Cavotricuspid Isthmus (CTI) dependent atrial flutter. Participants will be randomized to receive either AI-guided HPSD ablation at 50 Watts or conventional power settings at 30 Watts. Both arms will use the Carto 3D mapping system and the QDOT MICRO ablation catheter (Biosense Webster). An anatomically contiguous line will be created with \<6mm inter-lesion distance. After a standardized wait time of 30 minutes, ablation success will be assessed. The primary outcome is total radiofrequency ablation time. Secondary outcomes include procedural time, fluoroscopy time, safety outcomes, and 3-month freedom from recurrence. It is our expectation that HPSD will result in a shorter primary outcome.

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

50

Start Date

2024-06-03

Completion Date

2025-06-03

Last Updated

2024-05-09

Healthy Volunteers

No

Interventions

PROCEDURE

Ablation of the Cavo-tricuspid isthmus for typical Atrial Flutter

Durable block across the cavotricuspid isthmus by radiofrequency ablation.

Locations (1)

University of Calgary

Calgary, Alberta, Canada