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RECRUITING
NCT06408220
NA

Risk Assessment Evaluation for Identifying Participants at High Risk for Stomach Cancer

Sponsor: City of Hope Medical Center

View on ClinicalTrials.gov

Summary

This clinical trial evaluates the usefulness of various risk assessment tests, including Helicobacter pylori (H. pylori) breath testing, questionnaires, and endoscopies for identifying participants at high risk for stomach cancer. H. pylori is a bacteria that causes stomach inflammation and ulcers in the stomach. People with H. pylori infections may be more likely to develop cancer in the stomach. H. pylori breath testing can help identify the presence of H. pylori infection in a participant and help identify if the participant may be at a higher risk of developing stomach cancer. An endoscopy uses a thin, flexible lighted tube that is inserted inside the esophagus, stomach, and first part of the small intestine. This allows the doctor to see and look for abnormal areas that may need to be biopsied. Risk assessment including H. pylori evaluation, questionnaires, and endoscopies may help identify participants at high risk for stomach cancer and may be a useful screening tool for earlier stomach cancer diagnosis.

Official title: OUR Stomach Health Project: A Pilot Study to Evaluate the Feasibility of Stomach Cancer Risk Assessment for Early Detection and Secondary Prevention

Key Details

Gender

All

Age Range

40 Years - 80 Years

Study Type

INTERVENTIONAL

Enrollment

240

Start Date

2024-06-27

Completion Date

2029-10-09

Last Updated

2026-03-13

Healthy Volunteers

Yes

Interventions

PROCEDURE

Biopsy

Undergo tissue biopsy

PROCEDURE

Biospecimen Collection

Undergo blood sample collection

PROCEDURE

Breath Test

Undergo H. pylori breath test

PROCEDURE

Esophagogastroduodenoscopy

Undergo EGD

OTHER

Questionnaire Administration

Complete questionnaires

Locations (1)

City of Hope Medical Center

Duarte, California, United States