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Risk Assessment Evaluation for Identifying Participants at High Risk for Stomach Cancer
Sponsor: City of Hope Medical Center
Summary
This clinical trial evaluates the usefulness of various risk assessment tests, including Helicobacter pylori (H. pylori) breath testing, questionnaires, and endoscopies for identifying participants at high risk for stomach cancer. H. pylori is a bacteria that causes stomach inflammation and ulcers in the stomach. People with H. pylori infections may be more likely to develop cancer in the stomach. H. pylori breath testing can help identify the presence of H. pylori infection in a participant and help identify if the participant may be at a higher risk of developing stomach cancer. An endoscopy uses a thin, flexible lighted tube that is inserted inside the esophagus, stomach, and first part of the small intestine. This allows the doctor to see and look for abnormal areas that may need to be biopsied. Risk assessment including H. pylori evaluation, questionnaires, and endoscopies may help identify participants at high risk for stomach cancer and may be a useful screening tool for earlier stomach cancer diagnosis.
Official title: OUR Stomach Health Project: A Pilot Study to Evaluate the Feasibility of Stomach Cancer Risk Assessment for Early Detection and Secondary Prevention
Key Details
Gender
All
Age Range
40 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
240
Start Date
2024-06-27
Completion Date
2029-10-09
Last Updated
2026-03-13
Healthy Volunteers
Yes
Conditions
Interventions
Biopsy
Undergo tissue biopsy
Biospecimen Collection
Undergo blood sample collection
Breath Test
Undergo H. pylori breath test
Esophagogastroduodenoscopy
Undergo EGD
Questionnaire Administration
Complete questionnaires
Locations (1)
City of Hope Medical Center
Duarte, California, United States