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RECRUITING
NCT06408688
PHASE4

Safety and Modulation of Adaptive Immunity by Iscador® Qu Viscum Album Extract in Patients With Advanced, Recurrent or Metastatic Cancers Treated With Immune Checkpoint Inhibitors

Sponsor: University Hospital, Basel, Switzerland

View on ClinicalTrials.gov

Summary

The main objective of this study is to test if adding the mistletoe extract Iscador® Qu to regular cancer treatment with immune checkpoint inhibitors affects: * The immune system's ability to fight cancer * Safety of the treatment * How well the treatment performs against cancer * How the patient feels during treatment Researchers will compare patients treated with immune checkpoint inhibitors plus Iscador® Qu with patients treated with imune checkpoint inhibitors only.

Official title: Safety and Modulation of Adaptive Immunity by Iscador® Qu Viscum Album Extract in Patients With Advanced, Recurrent or Metastatic Cancers Treated With Immune Checkpoint Inhibitors - a Randomized Trial

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

100

Start Date

2024-06-24

Completion Date

2026-11

Last Updated

2024-12-27

Healthy Volunteers

No

Interventions

DRUG

Immune checkpoint inhibitors plus Iscador® Qu.

Standard cancer treatment plus subcutaneous injection of mistletoe fermented extract (Iscador® Qu) as per the summary of product characteristics.

DRUG

Immune Checkpoint Inhibitors

Standard cancer treatment.

Locations (4)

Kantosspital Baden AG

Baden, Switzerland

Universitätsspital Basel

Basel, Switzerland

Kantonsspital Baselland

Liestal, Switzerland

Tumor- und Brustzentrum Ostschweiz

Sankt Gallen, Switzerland