Clinical Research Directory
Browse clinical research sites, groups, and studies.
Mood and Decision-making in Methamphetamine Use Disorder
Sponsor: Laureate Institute for Brain Research, Inc.
Summary
In this project, the investigators examine behavior and associated brain activity during explore-exploit decision-making tasks performed pre- and post-modulation of affective state using autobiographical memory recall. The investigators hypothesize that a positive memory recall will reduce negative affective state, reduce explore-exploit biases and normalize the associated brain activity. The investigators propose a randomized double-blind, sham-controlled trial of positive autobiographical memory recall with 80 adults (n=40 per arm) with methamphetamine use disorder (MUD) currently involved in abstinence only treatment centers.
Official title: Modulating Explore-exploit Biases by Improving Mood in Adults With Methamphetamine Use Disorder
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
80
Start Date
2024-07-26
Completion Date
2027-07-01
Last Updated
2025-09-03
Healthy Volunteers
No
Conditions
Interventions
Mood modulation
Autobiographical memory recall designed to modulate mood and affective state by reminiscing about personal life events
Locations (1)
Laureate Institute for Brain Research
Tulsa, Oklahoma, United States