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RECRUITING
NCT06410300

Cardiopulmonary Monitoring in Lung Cancer Patients Receiving Combined Thoracic Radiotherapy and Immunotherapy

Sponsor: Bo Lu

View on ClinicalTrials.gov

Summary

The overall purpose of this study is to evaluate cardiopulmonary toxicity in patients with lung cancer (NSCLC or SCLC) undergoing combined thoracic radiotherapy ± chemotherapy and immunotherapy through timed monitoring and blood sample collection and to identify correlative biomarkers for predicting cardiopulmonary adverse events.

Official title: A Multi-Center Pilot Biomarker Study With Cardiopulmonary Monitoring in Lung Cancer Patients Receiving Combined Thoracic Radiotherapy and Immunotherapy

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

125

Start Date

2024-04-19

Completion Date

2030-04-19

Last Updated

2025-06-19

Healthy Volunteers

No

Conditions

Interventions

RADIATION

Curative Radiotherapy

Radiation dose of 45 Gy or higher

DRUG

Immunotherapy

checkpoint inhibitor per PI discretion

Locations (3)

University of Missouri - Ellis Fischel Cancer Center

Columbia, Missouri, United States

Rutgers Cancer Institute of New Jersey

New Brunswick, New Jersey, United States

University of Rochester Medical Center

Rochester, New York, United States