Clinical Research Directory

Impact of Intrathecal vs Intravenous Dexmedetomidine

Sponsor: Muhammad Ilyas

Summary

The purpose of this research is to evaluate the impact of intrathecal dexmedetomidine in comparison with intravenous route in patients undergoing cesarean section. Alternate hypothesis :Dexmedetomidine is more effective when given intrathecally as adjuvant to bupivacaine in elective cesarean section Null Hypothesis: Dexmedetomidine is more effective when given intravenously as adjuvant to bupivacaine in elective cesarean section Study Design: Randomized controlled trial Study setting: Watim General Hospital Study Duration: 18 months after synopsis approval Sampling technique: Simple random sampling Sample Size: Using the Open Epi program, a sample size of 60 patients (30 in each group) was determined with a 95% confidence interval and 80% power. Inclusion Criteria: * Pregnant women between ages 18-35 years * Belongs to ASA class I or II * Subjected to elective C-section Exclusion Criteria: * Any history of gastrointestinal disease diabetes, thyroid disease, hypertension, obesity, or anemia * History of alcohol or drug abuse; * Major complications of pregnancy * Patients have contraindication to spinal block or allergic to any of drug

Official title: Impact of Intrathecal Versus Intravenous Dexmedetomidine Adjuvant to Bupivacaine in Elective Cesarian Section

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