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NOT YET RECRUITING
NCT06412718

Validation of Human Drugs Target of Repurposed Drugs and Novel Therapies

Sponsor: IRCCS Ospedale San Raffaele

View on ClinicalTrials.gov

Summary

The cross-sectional observational clinical study related to rare eye diseases is a multi-center study in which the hypothesis is that neurokinin 1 receptor and/or substance P expression is increased in REDs associated with inflammation/pain. Moreover, the following alternative targets are: VEGF, PAX6 and pro-inflammatory cytokine. The following procedures are performed specifically for the study: samples of blood, tear fluid and impression cytology. Precisely during the ophthalmological exam performed according to normal clinical practice (uncorrected visual acuity, best spectacle corrected visual acuity, corneal topography, corneal pachymetry and the slit lamp pictures) investigator's team collect the samples of blood, tear fluid and impression cytology to evaluate the goal of the study.

Key Details

Gender

All

Age Range

18 Years - 99 Years

Study Type

OBSERVATIONAL

Enrollment

274

Start Date

2024-05

Completion Date

2026-04

Last Updated

2024-05-14

Healthy Volunteers

Yes