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The Effects of Different Loading Doses of Dexmedetomidine on The Bispectral Index-Guided Propofol Sedation in Patients Undergoing Advanced Upper Gastrointestinal Endoscopic Procedures: A Randomized Control Study
Sponsor: Theodor Bilharz Research Institute
Summary
Propofol is currently the most common drug used but has drawbacks like narrow therapeutic window and potential complications. Dexmedetomidine is an attractive alternative due to its unique properties like minimal respiratory depression. Studies are ongoing to find the optimal use of dexmedetomidine for these procedures. A combination of propofol and dexmedetomidine might be ideal, but the best balance between the two drugs needs further investigation.
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
52
Start Date
2024-05-01
Completion Date
2024-10-01
Last Updated
2024-05-16
Healthy Volunteers
No
Conditions
Interventions
Precedex (Dexmedetomidine) 200 MCG in 2 ML Injection
The Effects of Different Loading Doses of Dexmedetomidine on The Bispectral Index-Guided Propofol Sedation in Patients Undergoing Advanced Upper Gastrointestinal Endoscopic Procedures: A Randomized Control Study
C group: Patients received saline infusion over 10 minutes
the group will receive normal saline infusion over 10 minutes.
Locations (1)
Theodor Bilharz Research Institute
Cairo, Giza Governorate, Egypt