Clinical Research Directory

Inclusion Criteria: * Age \>= 18 years * Huntington disease genetically confirmed by the presence of at least 35 repeats of the CAG triplet in exon 1 of the HTT gene * UHDRS (Unified Huntington's disease Rating Scale) score \<= 5 with a diagnostic confidence score =4 * Absence of significant cognitive impairment MoCA \>=24 * Stable drug therapy in the 28 days prior inclusion and during the study * Without legal tutors or subordination * Affiliated to a health insurance system as required by the French law on biomedical research * Written informed consent for participation in the study Exclusion Criteria: * Inability to give free and informed consent for study participation * Significant hearing impairment * Participating to another study the day of enrollement * Persons benefiting from enhanced protection, i.e.persons deprived of their liberty by a judicial or administrative decision, adults under legal and finally patients in a vital emergency situation.