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RECRUITING
NCT06416371

Retinal Vessel Leakage in Cerebral Small Vessel Disease

Sponsor: University of Edinburgh

View on ClinicalTrials.gov

Summary

The goal of this observational study is to learn about leakage from retinal vessels in cerebral small vessel disease. The main questions it aims to answer are: * Does retinal vessel leakage occur in cerebral small vessel disease? * If it does, is the severity of retinal vessel leakage similar to the severity of cerebral small vessel disease generally? Participants will be tested using fluorescein angiography. This involves an intravenous injection of fluorescent dye, and is a very sensitive way to find leakage from retinal blood vessels. Participants will have already had brain scans and other examinations and tests to measure the severity of their cerebral small vessel disease. Our new retinal images will complement the information from these previous tests.

Official title: Retinal Vessel Leakage in Cerebral Small Vessel Disease: a Sub-study of the Mild Stroke Study 3

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

40

Start Date

2025-01-13

Completion Date

2029-02-15

Last Updated

2026-03-04

Healthy Volunteers

No

Interventions

DIAGNOSTIC_TEST

Fundus fluorescein angiography, with ultrawide field retinal imaging

Intravenous injection of sodium fluorescein for angiography of retinal blood vessels

Locations (1)

NHS Lothian

Edinburgh, United Kingdom