Clinical Research Directory
Browse clinical research sites, groups, and studies.
Brief ES for Recovery of Autonomic Function in CES
Sponsor: University of Liverpool
Summary
BESCES is a study that aims to explore the feasibility of intraoperative brief epidural electrical stimulation (ES) for patients undergoing routine decompression for cauda equina syndrome. In consenting patients, brief ES will be applied using a CE-marked SCS trial kit once sufficient decompression is achieved. In participants who do not recover function following decompression, brief post-op ES will be applied to see if can facilitate micturition and/or removal of the catheter. The study will assess: The feasibility of intervention. If brief ES can facilitate conduction in residual neurons. If brief ES can facilitate neuronal recovery
Official title: Can Brief Perioperative Epidural Electrical Stimulation Improve Recovery of Autonomic Function in Cauda Equina Syndrome
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
40
Start Date
2024-02-15
Completion Date
2026-09-15
Last Updated
2026-02-19
Healthy Volunteers
No
Conditions
Interventions
Brief ES at the time of decompression for cauda equina syndrome
In patients operated for acute cauda equina syndrome with autonomic dysfunction epidural ES will be delivered utilising SCS trial electrode. It will be delivered for 10 minutes caudal to compression site and for 60 mins cranial to compression site while the wound is closed and patient recovered.
Brief ES to facilitate mcturition/removal of catheter
In patients who do not fully recover function following decompression, brief ES will be applied before second micturition attempt.
Locations (1)
The Walton Centre NHS Foundation Trust
Liverpool, Merseyside, United Kingdom