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Autopsy and Photon Counting Computed Tomography to Evaluate Thromboses Related to Central Venous Catheters
Sponsor: Thomas Kander
Summary
Central venous (CVC) is essential in modern healthcare but unfortunately associated with complications, including thrombosis. In a recently published study, it was showed that 12 out of 12 deceased patients had subclinical CVK-related thrombosis (Rockholt et al.). To shed light on this problem, the current studies were designed. In sub-study 1, deceased patients with CVC who are referred for clinical autopsy are included. Before the autopsy, the deceased will be examined with a photon-counting computed tomography (CT) scan and the results will be compared. In sub-study 2, living patients with CVC who are referred for various CT scans without contrast, are included. After informed consent, the patient will be examined with the photon-counting CT, whose reliability has been validated in Part 1 and the incidence of subclinical CVC-related thrombosis will be reported.
Official title: Autopsy and Photon Counting Computed Tomography to Evaluate Thromboses Related to Central Venous Catheters (PHOTO CAT)
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
75
Start Date
2025-01-16
Completion Date
2028-06
Last Updated
2025-01-20
Healthy Volunteers
No
Conditions
Interventions
Diseased patients with an indwelling central venous catheter who is referred to autopsy
Photon counting CT is performed and the results are compared to the results of the autopsy
Living patients with an indwelling central venous catheter referred to a CT scan without iv contrast
Patients will be investigated using a photon counting CT. Prior to the investigation patients will be investigated with ultrasound. The results from the two modalities will be compared
Locations (1)
Intensive and Perioperative Care. Skåne University Hospital. Lund
Lund, Skåne County, Sweden