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RECRUITING
NCT06418308
PHASE4

Intrathecal Dexmedetomidine vs Epinephrine

Sponsor: Icahn School of Medicine at Mount Sinai

View on ClinicalTrials.gov

Summary

Several studies have shown that adding dexmedetomidine or epinephrine to single-dose spinal analgesia preparations improves the length and/or speed of onset of the sensory block and post-operative pain management without increased negative side effects. To date, however, no study has compared adjunctive intrathecal dexmedetomidine to adjunctive intrathecal epinephrine in single-dose spinal analgesia. The purpose of this study is to determine if adjunctive intrathecal dexmedetomidine is non-inferior to adjunctive intrathecal epinephrine in providing better single-dose spinal analgesia during cesarean section.

Official title: Comparison of Intrathecal Epinephrine Versus Dexmedetomidine as Adjuvants in Cesarean Section

Key Details

Gender

FEMALE

Age Range

18 Years - 55 Years

Study Type

INTERVENTIONAL

Enrollment

62

Start Date

2024-09-17

Completion Date

2026-03

Last Updated

2026-01-07

Healthy Volunteers

No

Interventions

DRUG

Dexmedetomidine

5 mcg of dexmedetomidine

DRUG

Epinephrine

200 mcg of epinephrine

DRUG

Standardized Spinal Mixture

Standardized spinal mixture of 10.25 mg hyperbaric bupivacaine, and 0.125 mg morphine.

Locations (1)

Mount Sinai Hospital

New York, New York, United States