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Intrathecal Dexmedetomidine vs Epinephrine
Sponsor: Icahn School of Medicine at Mount Sinai
Summary
Several studies have shown that adding dexmedetomidine or epinephrine to single-dose spinal analgesia preparations improves the length and/or speed of onset of the sensory block and post-operative pain management without increased negative side effects. To date, however, no study has compared adjunctive intrathecal dexmedetomidine to adjunctive intrathecal epinephrine in single-dose spinal analgesia. The purpose of this study is to determine if adjunctive intrathecal dexmedetomidine is non-inferior to adjunctive intrathecal epinephrine in providing better single-dose spinal analgesia during cesarean section.
Official title: Comparison of Intrathecal Epinephrine Versus Dexmedetomidine as Adjuvants in Cesarean Section
Key Details
Gender
FEMALE
Age Range
18 Years - 55 Years
Study Type
INTERVENTIONAL
Enrollment
62
Start Date
2024-09-17
Completion Date
2026-03
Last Updated
2026-01-07
Healthy Volunteers
No
Conditions
Interventions
Dexmedetomidine
5 mcg of dexmedetomidine
Epinephrine
200 mcg of epinephrine
Standardized Spinal Mixture
Standardized spinal mixture of 10.25 mg hyperbaric bupivacaine, and 0.125 mg morphine.
Locations (1)
Mount Sinai Hospital
New York, New York, United States