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[68Ga]Ga-Sa-DABI-4 PET Imaging of Stimulator of Interferon Gene Expression in Cancer Patients
Sponsor: First Affiliated Hospital of Chongqing Medical University
Summary
Stimulator of interferon gene (STING) protein plays a vital role in the immune surveillance of tumor microenvironment. Monitoring STING expression in tumors benefits the relevant STING therapy. This study will investigate the safety, biodistribution and potential usefulness of a novel 68Ga-labeled agonist (\[68Ga\]Ga-Sa-DABI-4) for noninvasive positron emission tomography (PET) imaging of STING expression in the tumor microenvironment.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
30
Start Date
2024-05-30
Completion Date
2026-12-31
Last Updated
2025-06-04
Healthy Volunteers
Yes
Interventions
[68Ga]Ga-Sa-DABI-4
Each subject receives a single intravenous injection of \[68Ga\]Ga-Sa-DABI-4.
Locations (1)
The First Affiliated Hospital of Chongqing Medical University
Chongqing, Chongqing Municipality, China